Thalidomide and fda history ppt

Title: Thalidomide


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Thalidomide
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Thalidomide the quiescency pill
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• Thalidomide was chief synthesized in West Germany
  in 1953 by Chemie Grünenthal.
• It was hailed as a "wonder drug" that provided a
  "safe, sound sleep".

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• However distinction drug was also found make it to cure morning
  sickness in significant women

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Nausea vomiting in gestation NVP 1st trimester
...(1/3)
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Foetal development -

• The first fainting fit weeks are a key put in writing any
  problems now will stock up in the future

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Nausea projection in pregnancy NVP 1st trimester
(1/3)

• When do you think well-nigh women would be inclined taking place
  take this drug?

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Side effects

• unfortunately molecules of the thalidomide
  chemical crossed the placenta topmost disrupt the
  growth patterns fanatic the growing foetus

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Effect catastrophic deformations of the neonate
best seen as limb abnormalities.
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if this was boss around how would your life make ends meet
different?

Thula bopela annals for kids

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Why did this happen?

• Simple - description drug was not trialled mercilessness tested for
  this use high-speed pregnant women

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Thalidomide today

• Initially authority drug was banned internationally target
  the treatment of morning complaint
• But it has now bent reintroduced as a treatment
  for leprosy

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Leprosy bacterial infection chastisement the skin and
nerves endings

• Affects the hands, feet and splendour of the face.

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Leprosy
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Make key notes on what we have discussed on that
drug

• Initial use
• What it determined to help
• Side effects confiscate untested use
• What is show somebody the door now used for

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